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Human B7-H3 Mouse IgG2a Wildtype Fc Amount:50 µg WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQL

SKU: 49362437853

4.6
USD250.00 USD291.00

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Description

WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQL

due to defective resorption of immature bone

TRID Tag: Mouse IgG2a GenBank Accession: NM_003841 SwissPro Accession: O14798 Expression Host: 293T Construction: Human TRAIL-R3 (S25-T161)-mouse IgG2a Fc MW (calculated): 42253

1038/s41577-022-00821-1

** Please note: For orders over 1 mg

Human B7-H3 Mouse IgG2a Wildtype Fc Amount:50 µg WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLB7 H3 is an orphan ligand in the B7 family. Its extended extracellular IgSF domain is unique within the family and is phylogenically found in primates only. B7 H3 is known as a co stimulatory and co inhibitory ligand, even though most studies indicate B7 H3 acts as an inhibitor for T cells functions. Consistent with the inhibitory notion, B7 H3 null mice exhibits an earlier onset of autoimmune disorders. P7105F contains all four extracellular IgV C

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