binding of isaac four souls card game Maestro Media: The Isaac: (2nd Edition) - Strategy Game, Officially Licensed, Ages 13+, 1-4+ Players, 30 Min and custom dividers The Binding of Isaac: Four

It looks like these Starter Commander Decks (SCD) will be the new take on that idea, although the commanders are all reprints from past sets

Mais strategy was all about duplicating Harpies with Elegant Egotist to Summon Harpie Lady Sisters , and Legendary Duelists: Sisters of the Rose has brand-new cards to help you multiply your Harpies and reward you for playing with the classic Harpie Lady Sisters card

These are worth quite a bit regardless of the card, so sleeve it up, price-check it, and consider grading it

You will be walking around looking for random encounters often in this game because that is the only way to progress through the game

Market Price $23.16 Holofoil Price updated Jul 29, 2026 Marnie (Secret) has dropped 13.0% since release

Other support cards have become available thanks to events and booster boxes like Future Horizon