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Basilisk Collar and Blind Obedience can provide some lifegain that we can use with Dawn of Hope

The reason for the huge price variation is due to grading

Normal combat damage happens with poison creatures but the player just doesnt gain a new poison counter when the trigger resolves

The majority of all Commander precons usually have three colors, especially in recent years, so to see an emphasis on two-color decks is a nice change of pace for the game at large

The artwork often determines this on the card or whether or not the card is foil (a shiny version of the card that is usually more expensive)

Dumping the counters on a Master Biomancer to make everything huge, or taking infinite turns with Sage of Hours or going to Hydra town this guy does it all