Propargy-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Size:25mg Product Name Sulfo-CA-BODIPY Synonyms BODIPY

Product Name Sulfo-CA-BODIPY Synonyms BODIPY Halotag Ligand Impermeable CAS Number N/A Related CAS N/A Molecular Formula C27H40BClF2N3O6S Molecular Weight 618

The conventional maleimidocaproyl (MC) unit is replaced by Mal-Propionyl-PEG4 moiety to enhance aqueous solubility

43 Purity (HPLC) >= 95% Physical Appearance Dark Solid Optical Properties Abs/Em Maxima: 494/585 nm Solubility DMSO

SOLU-KNEX® is a registered trademark of Tenova Pharmaceuticals

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

Propargy-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Size:25mg Product Name Sulfo-CA-BODIPY Synonyms BODIPYSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing