Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-Exatecan probe Product Name Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS

Product Name Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C84H109FN12O28 Molecular Weight 1753

314 SMILES O=C1N(CC2=C(NCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl N-[3-(piperazin-1-yl)propyl]carbamate Synonyms 1-(3-N-Boc-aminopropyl)piperazine CAS Number 874831-60-4 Related CAS Molecular Formula C12H25N3O2 Molecular Weight 243

Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection

Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB Synonyms CAS Number Related CAS Molecular Formula C53H72N8O12 Molecular Weight 1013

Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-Exatecan probe Product Name Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I