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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg Product Name DOTA-tris(t-Bu)ester-C2-propanamido-maleimide Synonyms CAS

SKU: 8215968486

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Description

Product Name DOTA-tris(t-Bu)ester-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C37H63N7O10 Molecular Weight 765

644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The conventional maleimidocaproyl (MC) unit is replaced by Mal-Propionyl-PEG6 moiety to enhance aqueous solubility

Product Name Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H136N14O23 Molecular Weight 1734

297 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg Product Name DOTA-tris(t-Bu)ester-C2-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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