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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE cy3 which can be conjugated to

SKU: 56776115087

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Description

which can be conjugated to target protein ligands through straightforward chemical reactions

Product Name Lenalidomide-CO-PEG3-Cl Synonyms Lenalidomide-4'-CO-PEG3-Cl CAS Number n/a Related CAS Molecular Formula C22H28ClN3O7 Molecular Weight 481

Product Name Lenalidomide-PEG5-OH Synonyms Lenalidomide-4'-PEG5-OH CAS Number n/a Related CAS Molecular Formula C23H33N3O8 Molecular Weight 479

852 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C50H72N8O18 Molecular Weight 1073

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE cy3 which can be conjugated toSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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