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Degrader building block for targeted protein degradation
Product Name DOTA-tris(t-Bu)ester-hexyne Synonyms CAS Number n/a Related CAS Molecular Formula C34H61N5O7 Molecular Weight 651
Product Name Thalidomide-propargyl-C1-OH Synonyms Thalidomide-4'-propargyl-C1-OH CAS Number n/a Related CAS Molecular Formula C17H14N2O5 Molecular Weight 326
Product Name Pomalidomide-CO-C5-Br Synonyms Pomalidomide-4'-CO-C5-Br CAS Number 2227423-38-1 Related CAS Molecular Formula C19H20BrN3O5 Molecular Weight 450
722 SMILES: [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCCN=[N]#N Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
SHP099 Size:5mg Degrader building block for targetedSHP099 is a highly potent (IC50 = 0. 071uM),selective and orally bioavailable small molecule SHP2 inhibitor. The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism. SHP099 suppresses RASERK signalling to inhibit the proliferation of receptor tyrosine kinase driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models. Product Name SHP099 Synonyms CAS Number 1801747 42 1 Related CAS Molecular Formula
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