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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB nitrogen facilitating reliable ADC synthesis for

SKU: 46180646801

4.7
USD195.00 USD230.00

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Description

facilitating reliable ADC synthesis for oncology research

054 SMILES [2H]C([2H])([2H])OC1=CC=CC=C1Br Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C64H87FN10O18 Molecular Weight 1303

Product Name Thalidomide-O-acetamido-C2-alkyne Synonyms Thalidomide-4'-O-acetamido-C2-alkyne CAS Number n/a Related CAS Molecular Formula C19H17N3O6 Molecular Weight 383

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB nitrogen facilitating reliable ADC synthesis forSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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