Azide-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg Product Name 4-(methoxy-d3)benzonitrile Synonyms 4-(²H3)methoxybenzonitrile

Product Name 4-(methoxy-d3)benzonitrile Synonyms 4-(²H3)methoxybenzonitrile CAS Number  1404321-27-2 Related CAS Molecular Formula C8H7NO Molecular Weight 136

Product Name 2-Chloro-6-methyl-N

366 SMILES OCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

the reaction product is stable

The payload is Exatecan

Azide-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg Product Name 4-(methoxy-d3)benzonitrile Synonyms 4-(²H3)methoxybenzonitrileSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing