Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE dbco 148 Purity (HPLC) >= 95%

148 Purity (HPLC) >= 95% Solubility DMSO

301 SMILES OCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

054 SMILES [2H]C([2H])([2H])OC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

171 Purity (HPLC) >= 95% Solubility DMSO

1039/d4cb00209a

Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE dbco 148 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate