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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Alexa Fluor 488 81 SMILES Cl

SKU: 25068449585

4.4
USD245.00 USD287.00

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Description

81 SMILES Cl

Haven't got a glue: Protein surface variation for the design of molecular glue degraders

Product Name Pomalidomide-PEG5-C2-amine HCl Synonyms Pomalidomide-4'-PEG5-C2-amine HCl CAS Number 2357117-23-6 Related CAS Molecular Formula C25H37ClN4O9 Molecular Weight 573

Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C96H159N13O29 Molecular Weight 1959

064 SMILES [H]C(=O)C1=CC=C(Br)C(OC([2H])([2H])[2H])=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Alexa Fluor 488 81 SMILES ClSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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