Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9

S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9 Related CAS Molecular Formula C27H34N4O5S Molecular Weight 526

406 SMILES [N-]=[N+]=NCCCCCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The photostability and brightness of CPY make it a valuable tool for detailed imaging of cellular dynamics

Product Name DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C98H147N13O24 Molecular Weight 1891

TCO (trans-cyclooctene) is a strained alkene used in click chemistry for bioorthogonal reactions like iEDDA (inverse electron-demand Diels-Alder)

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I