Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan cp 91 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC)

91 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-NHS Synonyms CAS Number 170908-81-3 Related CAS Molecular Formula C20H31N5O10 Molecular Weight 501

937 Purity (HPLC) >= 95% Solubility DMSO

982 Purity (HPLC) >= 95% Solubility DMSO

321 Purity (HPLC) >= 95% Solubility DMSO

Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan cp 91 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase