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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae DOTA bifucational chelator containing an

SKU: 12914069975

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Description

DOTA bifucational chelator containing an amine group

BG-Ac is a SNAP-tag substrate used as a small-sized label for comparison with other SNAP-tag substrates

m-PEG8 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to further increase aqueous solubility

5(6)-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

164 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae DOTA bifucational chelator containing anSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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