If youre looking to kill the enchanted creature, that is
In Commander, this effect is going to be completely useless in decks that dont run Relentless Rats / Seven Dwarves / Persistent Petitioners
Quandrix + Temporal Trespass Delve works especially well with Cascade because reducing the amount of mana you actually pay does not reduce the cards mana value
Raking Canopy Raking Canopy doesnt prevent flying creatures from attacking you or take away their flying abilities
This post will contain spoilers for Final Fantasy X , though it's been almost 24 years, so
Now, board wipes and non-targeted removal still work, and enchantments like Nowhere to Run can nullify Wards, but this is still a strong card that I expect to see get played a lot in Standard and especially Limited